PRO33 RTP OPTIONS

The PlA1/PlA2 polymorphism lies in the gene for the β3 (GPIIIa) subunit of αIIbβthree (GPIIb-IIIa). This integrin serves for a receptor for adhesive proteins fibrinogen and von Willebrand issue which is essential to the cohesive Houses of platelets. Recognition of these proteins as soluble ligands needs αIIbβthree to be activated by exposing p